Microsoft have confirmed the issue as fully mitigated.

Further update from Microsoft

Impact Statement: Starting at approximately 21:56 UTC on 18 Jul 2024, a subset of customers may experience issues with multiple Azure services in the Central US region including failures with service management operations and connectivity or availability of services. Current Status: We are aware of this issue and are actively investigating. The next update will be provided in 60 minutes, or as events warrant.

https://app.azure.com/h/1K80-N_8

We have had success initiating a rolling restart of all instances within the region. We await further updates from Microsoft, but we have normal levels of redundancy now back in place.

Microsoft have confirmed there is a region wide issue

Investigating alerts in the Central US region
We’re investigating alerts for issues with services the Central US region. We'll provide additional updates shortly.

We are experiencing multiple disk failures in the Azure US central region. These are causing some disruption to services as it appears to be affecting multiple machines but at different times resulting in the machines locking up at random intervals.

Traffic is routing around the machines as required, but some calls may be experiencing some disruption in the period between the disk failing and calls being re-routed around the failed instnace.